If you are a raider you should already know when I big spike of damage is about to happen, so being pro active and knowing the mechanics of the fight really assist in the decision making of a popping a cooldown. I usually do it when I know that heals aren't sufficient or I'm anticipating a really big spike of damage. All in all, its simply anticipating the mechanics of an encounter and knowing the calibur of healer that you have; even then its hard to gauge that.
Good Luck!





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