I personally think that for the majority of encounters the best options are Satrina's and the Glyph of Indomitability. For maximum efficiency though you have to switch for encounters, for example if there is predictable burst that can be avoided with a little bit of magic damage a Satrina Glyph combo shines. For just pure physical damage like Marrowgar I would use a Satrina, Black Heart combo for maximum EH.
With around 45% magic damage and higher in what will kill you I could see a double Satrina combo coming in handy. And finally for avoidance favoring bosses like Saurfang or the gunship captain double avoidance trinkets come in handy.


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