First question: are you 2h or dual wielding?
The balance works out pretty easily. 2-disease methods are stronger now with dual wielding, particularly glyphing Oblit, as your OB's and BS's really hit harder. The trade off is that the two disease rotation is not nearly as easy or static. The single disease method, which is ideal with glyphed HB is great on AoE packs regardless, and the rotation is simple, but for the sake of maximizing threat, it won't hold up quite as well (though it will almost certainly still do the job).
I actually favored splitting them. I glyphed HB, and for aoe packs I just leaned on HB and BB heavily, no PS, no IT, no Pest, no BS, and OB only to proc Rime if HB was on CD. Then on bosses and big single target fights I ironed out a dynamic 2-disease setup (but rotation is a bad word for it, it doesn't smooth out easily enough for you to follow a simple bi-phasic cast sequence, not that I favor sequences anyway). I did figure out ways to not use IT often enough and just applied FF through HB instead. It did make things a little easier but it ended up using Blood Tap to find some FU pairs in weird places.