In my opinion, it depends on the socket bonus and the socket colors.
When I gem for progress, I leave out boni like +8 dodge or +6 def, I also don't even try to reach my +6 stamina bonus, when there is a red and a yellow socket in it.
Assuming that there is a +9 stamina bonus for ex. a blue and a red socket, it may be worth taking it.
On my aggro gear however, it's no real problem to go for some boni since hit/sta or exp/sta are very sensible choices. I even reccomend not to waste some potential by not using these boni. Anyway if your goal is to max out your HP pool, better drop some.