Since my last reply I have upgraded to an 28" 1920x1200 display instead of my old 22" 1650x1050, which helps a lot.
I try to keep the top part of my screen as empty as possible, it is not an area that I immedeatly look to in any case.
To the left middle you see elkano buff bars (abbr: ebb) (although satrina's looks very good, elk's are so customizable). Bottom ones are my own buffs, weapon enchant above it, pet buffs above that.
On top of my own player frame I have another ebb bar concerning self-cast buffs/trink procs. Above it there's a quartz proc module.
Quartz castbar with the GCD bar on top of it, it used to be above it, now I'm gonna go old school again and see if this compacter form is better.
Above the cast bar is an additional swing timer bar for my melee chars.
Above that swing bar is the target target (not shown, dummies don't target. )
Sexycooldown for cooldown monitoring, I should configure it a little more, because I do have it, but pay not enough attention to it (partly because my bars are right below it with the cooldowns (did I make sexycooldown redundant? =X).
Quartz debuff tracking. Another EBB bar below the target frame listing buffs. To the right (not currently shown) another EBB bar giving info on debuffs on target that are benificial (stuns, crit modifiers, thunderclap etc).
Left bottom Prat, currently with the whisper window open (I used to have whisper addons, but most bugged out, now I just use an additional whisper window to not miss any whispers).
Sexymap. Next to it is grid, though when in raid. Next to that, omen when shown.
Middle/top Digits and rangedisplay (extremely useful addon noone ever seems to talk about especially since range is important for ANY class).
Plus MSBT modded as clean as possible.
Yes, I did use a viewporter. But since the bottom row is (when raiding) totally full of addons it doesn't interfere with any viewable terrain.
If you got anything to add, I would love to hear it, I try to get my UI as clean as possible. In addition, do I really have use for that cooldown bar? I know it's usefull, but I fail to properly utilize it at the moment, it seems.