Visually very appealing, 8/10
The cooldown bar seems to be a bit too long. i would adjust the height to that of the hud. Furthermore, having all your information in the bottom part of the screen it seems strange to place the tooltip in the top left corner. Button arrangement could be a bit more streamlined. I really can't see very well what buffs you have there but i am sure there is the possibility to trim that to buffs you want to see (devotion aura for a mage?). And lastly the gap between your target/player/targettarget/etc frames and the two boxes on the left and right are not the same width. Aim for perfection!
Sadly i have to fit everything into a 1280x1024 screen
25man raid, infight:
Changes since this screenshot:
-moved MT-frames over the omen frame (bottom left) and removed backdrop.
-filtered Flask of lesser resistance out of EBB and added it to the auracle flask tracker (stoneblood/resistance/rage)
-trimmed absored and resisted Parrot messages
-removed rank information from buffbars
-swapped standard nameplates of mobs with CaelNameplates and changed font to fit the general ui font.
The space to the right of the minimap is a "macro workspace". Since i didnt need any special macro for anub, there is nothing visible but one icon which belongs to an auracle debuff tracker. It shows missing debuffs on the target. In this case a missing demoshout/roar.