Just a personal taste, i really dont like X-pearl, but there is nothing wrong in there. Just wondering where are you going to fit Grid/Healbot/Raid frames in there. Like the nameplates, and you should considering having a addon for tooltips, like tiptop or something like that. For the buffs/debuffs use Satrina buff frames. I think you can also input in Xpearl, the buffs/debuffs of your target.
Iīll give a 6.5 (because of X-pearl), otherwise probably a 7
http://www.youtube.com/watch?v=YfqyhigpAho - (UI in action 10/25 man - WIP)