From what I've seen and done myself, there really isn't a tank weapon enchant right now. I've just picked up a Titanium Weapon Chain and have been using that. In the next patch(hopefully next week) there is a new enchant that will be "THE" tanking enchant. It's +75 stam, and should be relatively cheap(12 Dream Shards). I'm sure in future content patches there will be more weapon enchants, but right now there is not anything that great.
I currently use Accuracy on my weapon, and doubt I will use the +75 stamina enchant. With the content out there, I don't think there is much reason to stack health above 30k unless you are main tanking Sartharion with drakes up. So until then, stacking more offensive stats and staying above 30k health.
Any idea on how much of a threat increase you get using a fast dps weapon vs a tanking weapon like Last laugh.
I used Hatestrike for a short while until a Red Sword of Courage dropped for me, of course it will generate a little bit more threat because of the offensive stats on it. You do lose a lot of defensive stats though, defense being a major one.