Pre-patch WA and Incite were > all. HR was not necessary.
Gag Order is useful for Al'akir HC and Nef HC
Safeguard is a must-have imo, especially in 10s. There are at least like 3 situations at every encounter where you can use it.
IV is completely useless
Thunderstruck is kinda necessary in 2 ways. Rend is always a TPS win. You can reapply rend with TC so you do not lose a GCD without damage. TC is refreshed and after 3 TCs you can use SW. I'm pretty positive that this is a great TPS win maybe more worth than HR.
Incite 1/3, Cruelty 0/2, HR 2/2, WA 3/3, DW 3/3 ( skipping revenge and imp revenge )
with 5% crit --> 38016 TPS
This is not that much of an increase.
And it is a huge difference if you calculate misses etc or not. SS will always be on higher priority than Devastate or anything else no matter what spec you have. So if you lose GCDs by Dem shout,TC, missed TC(-->Rend),missed shouts or anything else, it will cripple your Dev amount over a 60 seconds cycle but it wont hurt your SS at all. And overall it does not matter if you have 10% miss from a TPS pov, it may hurt more if 1 SS misses but in a spreadsheet the value loss of both will be the same as you use Dev way more often. Both values will be crippled by 10%.
The only argument is that less devastate will proc less SS. But this increaseas the value of Rev and another reason why I prefer a heavy Rev/SS build. Rev cannot be dodged or parried and procs SS.
And I am pretty sure if you do keep this in mind in a priority system, HR+Incite will be ahead of DW+WA. And to answer your question, I will never skip Safeguard. You could skip Rev and skill HR but this cripples your cleave. Thunderstruck is in my eyes too powerful to skip. I would consider dropping Blood craze to get points for DW but as long as my TPS is not that much of a problem, utility and survivability > TPS.
And do not forget the most important thing why I highly prefer a HR/Cruelty heave build. SS scales better than any other skill. And DW proc ammount will always stay the same and only scales with avg weapon damage.