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In the transition, all dps is on the raging sprits (of course a range has to be assigned kill the orbs too, but they go down fast so he/she can target switch pretty easily) and the OT is off with the horror and ghouls holding them away from the raid and letting the plague kill them off. When the last one dies the OT normally gets the plague and before he runs into the raid to grab a spirit, the plague gets dispelled into the air.
This, watch your range and make sure the cleanser is nowhere near the OT when he/she dispells.