I use Bartender to format my action bar into the right columns and rows, then Button Facade to skin it. I use eePanels to create the lines to separate my add-ons with the blue lines.
Here is a link to my thread for my UI: http://www.tankspot.com/forums/f211/...byssul-ui.html
I was looking at your UI pic, and im just wondering what action bar adodon it is you are using? Ive been lookign all over curse and wowinterface and cant seemt o find a matching design. Also can i ask the name of the addon that created the lines accross your screen separating omen ect?
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