I currently have the easily obtainable
Axe of the Sen'jin protector, and am in a guild that is working on finishing Naxx 10. I'm debating whether it's worth it to put blood draining on the Axe, and whether or not
Slayer of the Lifeless would be an upgrade. Slayer is certainly better EH, and the axe is probably higher threat (although slayer is a lot faster, for what that's worth.
How do you decide at what point a non-axe (or equivalent weapons for humans and dwarves) is an upgrade, for that matter?