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Main tank takes normal damage from melee attacks and nature damage from poison shock (frontal cone). Assuming no one is in front of boss, then they take normal damage from adds and nature damage from web wrap.
Stack hots on tank, cleanse poisons asap and save CDs for enrage and time them for web spray. Its one of the few fights in naxx that I like to stack stam and armor for. We don't bother to stop dpsing and it hasn't been an issue.
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