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Personally, I use a number of shift + cominations on the keys that I can't quite reach with my keyboard hand.
Defensive Stance.
I use Q for revenge, Shift + Q for Intervene, E for spell reflect, Shift + E for Shield Slam, and Shift + R for Concussion Blow.
Of course there are other buttons that apply to these bindings in other stances, and some stay the same or change depending on if I'm Prot spec or not.
Hope this helps a little.
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