Just finished this UI for 1680x1050 for my tank. Wanted to try and keep the middle mostly clean. Still haven't used it in a raid so will have to see how it works.
Aloft - nameplates and aoe threat
Bartender4 - for my action bars
CBH Viewpoint - the black bar on the bottom and top
Cooldowns - adds a cooldown timer to my action bars
Digits - adds that digit percentile above my actions bars to see my health and rage easier
Elkano Buffbars - buffs on the left, debuffs on the right
Fubar - runs along the top for easy access to addons and information
Grid - grid is between my minimap and omen on the bottom right
Mik Scrolling Combat Text - for my sct
Omen - for threat
Pitbull4 - unit frames
Prat - for my chat
simpleMiniMap - my minimap